The results demonstrated consistent expression patterns between COVID-19 patients with Omicron infection and healthy individuals for the 10 hub genes (OAS1, IFI44, IFI44L, MX1, OAS3, USP18, IFIT1, RSAD2, IFI27, and ISG15) (Figure 4A–J). The gene discussed is IFI27; the disease is COVID-19.