In the recent studies regarding neuroprotective therapy for glaucoma, in a mouse model of acute RGC damage caused by optic nerve crush (ONC), and with chronic RGC degeneration obtained by intracameral injection of microbeads that induced ocular hypertension, orally administered NR removed retinal inflammation, as shown by immunofluorescence staining for glial fibrillary acidic protein (GFAP). This evidence concerns the gene GFAP and glaucoma.