A rare variant was reported at the ATPase secretory pathway Ca2+ transporting 2 (ATP2C2) gene [53] or sprouty RTK signaling antagonist 1 (SPRY1) gene [54], and a 452.4 Kb de novo heterozygous micro-deletion in chromosomal region 1p34.3 in a patient with dyslexia and attention-deficit/hyperactivity disorder was reported [55]. This evidence concerns the gene SPRY1 and dyslexia.