Conversely, carcinomas with low GATA3 expression are positive in less than 10% of cases, including gastric and colorectal adenocarcinoma, endometrial adenocarcinoma, hepatocellular carcinoma, cholangiocarcinoma, prostatic adenocarcinoma, and thyroid carcinoma [59]. The gene discussed is GATA3; the disease is hepatocellular carcinoma.