In our meta-analysis, the subtypes of UC with GATA3 expression in the overall invasive UCs were adenocarcinoma, adenoid differentiation, lymphoepithelioma-like, sarcomatoid, small cell neuroendocrine carcinoma, squamous cell carcinoma, squamous differentiation, signet ring cell carcinoma, and undifferentiated subtypes. The gene discussed is GATA3; the disease is signet ring cell carcinoma.