And the KEGG analysis revealed the top 30 biological pathways, including those involved in lipid metabolism and atherosclerosis, Kaposi’s sarcoma-associated herpesvirus infection, AGE-RAGE signaling pathway (Figure 4A), NF-κB signaling pathway (Figure 4B), IL-17 signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, and HIF-1 signaling pathway (see Figure 3B). The gene discussed is TNF; the disease is atherosclerosis.