The ribosomal protein S26 (RPS26) functions as a checkpoint for T lymphocyte survival and homeostasis in a p53-dependent manner, as reported by Chen et al. [23], and Zhao et al. [24], who demonstrated its upregulation in acute lymphoblastic leukemia (ALL) through qRT-qPCR analysis. Here, TP53 is linked to acute lymphoblastic leukemia.