Various autoantibodies are commonly found in the blood of individuals with polymyositis and dermatomyositis, including anti-Rho-1 and anti-SAE antibodies in polymyositis and anti-Mi-2, anti-MDA5, anti-NXP2, and anti-TIF1 antibodies in dermatomyositis. The gene discussed is IFIH1; the disease is polymyositis.