One patient had increased bilirubin (both total and direct), and this was found by us after observing in this patient’s history an adverse reaction to risperidone (lethargic state), which prompted pharmacogenetic testing that showed SNPs in SLC15A2, SLC22A1, SLCO1B3, ABCB1, and ABCC2 genes (the latter is linked to Dubin–Johnson syndrome). This evidence concerns the gene ABCB1 and Dubin-Johnson syndrome.