HTR2B and Anxiety: Viloxazine increases activity in the prefrontal cortex, possibly via differential actions on 5-HT receptors: antagonistic on 5-HT2B and agonistic on 5-HT2C receptors, and also acts on the norepinephrine transporter [62],—causing an important modulation of the cortico-basal tracts involved in the cortical control of the enlarged ASD amygdala [29,30,31], with improvement of the fear and anxiety symptoms which are present in a majority of ASD kids.