ACO1 and endometrial carcinoma: Quercetin also decreases the proliferation and cell migration of HEC-1-A endometrial carcinoma cells, where quercetin increases ROS production and transferrin receptors and reduces mitochondria membrane potential, aconitase 1 (an iron regulatory protein also known as iron-responsive element-binding protein 1, IREB1), GPX4, and SLC7A11 levels [23] (Figure 5).