Interestingly, all our findings involving an association with the risk of developing Chagas cardiomyopathy are within the C haplotype (HHC), according to Mummidi et al.: rs2734648 (T), rs1799987 (G), rs1799988 (T) and rs1800023 (G), this haplotype seems to induce a low transcriptional activity in Jukart cells (T lymphocyte lineage derived from leukemia), while in Nk cells (CD56+) and CD16+ it presents a high activity [41,42]. This evidence concerns the gene NCAM1 and leukemia.