ADIPOQ and asthma: As for children, some studies have reported that a low-calorie diet, exercise, and counseling can reduce exercise-induced bronchospasm with a significant reduction in post-exercise FEV1 drop [39] and can improve FEV1/FVC, reduce asthma symptoms, and increase adiponectin levels [40], suggesting that the asthma phenotype and obesity onset are key factors for the clinical improvement of patients.