IGHE and obesity due to melanocortin 4 receptor deficiency: For example, adult patients with eosinophilic asthma, high levels of IgE, and obesity who underwent bariatric surgery have reported improvements in their lung function (forced expiratory volume in 1 (FEV1) and forced vital capacity (FVC)) one year after the surgical intervention [35,36], control of asthma symptoms or remission [35], and decreased use of inhaled medications compared to patients with late-onset asthma or with normal serum IgE levels [35,36,37,38].