Hepatic transaminases, such as aspartate aminotransferase (AST) and alanine aminotransferase (ALT), as well as the AST/ALT ratio (the so-called “De Ritis” ratio), were shown to be associated with all-cause mortality in various clinical settings, such as patients with cancer, arterial hypertension, pulmonary embolism and sepsis [9,10,11,12,13,14]. The gene discussed is GPT; the disease is cancer.