A total of fifty patients were excluded due to the following reasons: NT-proBNP < 220 pg/mL (n = 16), significant coronary artery disease (n = 18), chronic thromboembolic pulmonary hypertension (n = 1), and cardiac amyloidosis (n = 15). The gene discussed is NPPB; the disease is chronic thromboembolic pulmonary hypertension.