miR-214-3p can inhibit the expression of cathepsin B, regulate the levels of anti-apoptotic bcl-2 and pro-apoptotic proteins Bax and caspase-3, decrease the levels of ROS and MDA, increase the proportion of SOD, reduce the apoptosis and oxidative damage of AC16 cells stimulated by LPS, and improve myocardial injury caused by sepsis [68]. This evidence concerns the gene CASP3 and Sepsis.