RB1 and nonpapillary renal cell carcinoma: Using the UALCAN web portal (http://ualcan.path.uab.edu, accessed on 19 August 2023), which allows analyzing gene expression based on TCGA RNA-Seq data [26], we estimated expression changes of CTDSP1, CTDSP2, CTDSPL, and RB1 in two major molecular subtypes of ccRCC, namely ccA (clear cell type A) and ccB (clear cell type B) (Figure 3A–D).