IFNG and granular corneal dystrophy type II: Immune signatures are unique in that (1) diphencyprone induces the strongest immune responses, as measured by innate immunity (IL-1α, IL-8), Th1 (IFN-γ, CXCL10), Th2 (IL-5, CCL11), Th17 (LL37), and regulatory T cells (FoxP3, IL-34, IL-37), and (2) dust mites induce modulation of the Th2 pathway, suggesting the heterogeneity of ACD pathogenesis.