A chimeric bovine papillomavirus (BPV) VLPs displaying MUC1 induced MUC1-specific CTL in a human MUC1 transgenic mouse model and impaired, or eradicated in few mice, tumor growth induced by RMA-MUC1 cells (a T cell lymphoma line) in this mouse model [178]. The gene discussed is MUC1; the disease is neoplasm.