In addition, in the PAH group, the concentration of Ang-(1-7) in lung tissue (0.60 ± 0.23 vs. 0.83 ± 0.029 pmoles/mL) and serum (0.59 ± 0.068 vs. 0.84 ± 0.49 pmoles/mL) decreased compared with the control group (p < 0.05). This evidence concerns the gene ANG and pulmonary arterial hypertension.