AGT and pulmonary arterial hypertension: We showed that PAH increased Ang-II concentration in lung tissue (0.78 ± 0.06 vs. 0.47 ± 0.06 pmoles/mL) and serum (1.21 ± 0.16 vs. 0.75 ± 0.064 pmoles/mL) compared with the control group (p < 0.05).