Unlike what has been repeatedly reported in axenic cultures, where more than 90% of the activity is due to EhCPs1, 2, 5 and 7, a study aiming to evaluate the expression of the CP genes of E. histolytica during the formation of amoebic liver abscesses by real-time PCR, found that other EhCPs increase their expression depending on the experimental model: Ehcp-a3, -a4, -a10 and -c13 during infection in gerbils and mice and Ehcp -b8 and -b9 only in gerbils [110]. This evidence concerns the gene CP and Liver abscess.