ABCG1 and acute disseminated encephalomyelitis: Simple effect analysis showed that ABCG1 gene expression was significantly decreased in the brains of mice in the ADC group compared with the WTC group (p < 0.0001); moreover, aerobic exercise significantly increased ABCG1 gene expression in the brains of mice in the ADE group compared with the ADC group (p < 0.05).