Cystic fibrosis (CF) is an autosomal recessive disease caused by variants in the cystic fibrosis transmembrane conductance regulator (CFTR) protein, a chloride and bicarbonate channel located on the apical side of epithelia, where it plays a critical role in maintaining the electrolyte and fluid balance of the surface liquid layer [1,2]. This evidence concerns the gene CFTR and cystic fibrosis.