When WT or CCN2-EGFP TG mice were placed on a CDAA-HF diet for up to 7 weeks, there were no significant differences in body weight, liver weight, or expression of fibrotic genes, lipid metabolism genes, and proinflammatory genes between the two mouse strains (Supplementary Figure S1), further confirming that CCN2-EGFP TG mice were comparable to WT mice. The gene discussed is CCN2; the disease is hydrops fetalis.