Gene expression-based clustering analyses of YAP1 point mutations have revealed that YAP1 fusion meningiomas resemble low-grade NF2 mutant meningiomas based on the up-regulated genes, whereas, based on the down-regulated genes, YAP1 fusion meningiomas cluster with high-grade NF2 mutant meningiomas [6,13]. The gene discussed is NF2; the disease is meningioma.