Figure 6B,C demonstrate that the percentage of cells expressing the CD206-PE fluorescent emission reached 14% in monocytes–FaDu compared to 0.27% in FaDu alone, confirming the expression of CD206 by macrophages and a differentiation of monocytes into an M2-like phenotype initiated by cancer cells. Of note, 14% of CD206-positive cells in the monocytes–FaDu condition represent all macrophages that infiltrated the spheroids, as we reported a similar percentage of CD68-positive cells in the same coculture condition (as documented in Figure 6A). This evidence concerns the gene MRC1 and cancer.