Tumor infiltration in Bruch’s membrane, an extracellular matrix between the retinal pigment epithelium and the choroid, showed a positive correlation with FLT3LG and MCP-1 (in aqueous and vitreous humor), and IL-8, IP-10, MIP-1α, and PDGF-AA (in vitreous humor) [126]. Here, FLT3LG is linked to neoplasm.