YAP1 and neoplasm: In vitro assays employing, for instance, the EAC cell line SKGT-4 (which shows intrinsically high levels of YAP expression) and Flo-1, as well as an in vivo xenograft mouse model, revealed anti-tumor effects through the inhibition of YAP/TEAD-transcription-associated proliferation and an increase in tumor cell death.