GH1 and acromegaly: Other causes of acromegaly are multiple endocrine neoplasia-1, McCune–Albright syndrome, ectopic pituitary adenoma with a sphenoidal location or in the parapharyngeal sinuses, iatrogenic excess of growth hormone, excessive secretion of central growth-hormone-releasing hormone (GHRH) (hamartoma, choristoma or ganglioneuroma) and peripheral (small-cell lung cancer, medullary thyroid carcinoma, pheochromocytoma, adrenal adenoma, insulinoma) [8].