NR0B2 and neoplasm: The structure–activity relationship (SAR) of a series of new diarylmethylphosphonates combining SHP and thiourea/urea moieties (Figure 12) showed that derivatives based on thiourea, unlike urea, do not exhibit cytotoxicity towards M-Hela, MCF-7 and HuTu80 tumor cells, with the exception of compound 18c.