IL6 and Alzheimer disease: A genotype effect on Il6 mRNA expression was observed [F (1,28) > 7.703; p < 0.01], with an overall decrease in Il6 expression in 3×Tg-AD female astrocytes compared to non-Tg (WT) female and 3×Tg-AD male groups (uncorrected Fisher’s LSD post hoc test; */##p < 0.05/0.01; Figure 1E).