NQO1 and Leber hereditary optic neuropathy: We sequenced NQO1 in our cohort and found that most of the LHON subjects were homozygous wild type; only two individuals were heterozygous for the c.559C>T/p.Pro187Ser polymorphism and one for the c.72G>A/p.Glu24Glu synonymous change (rs689453) [21] (Table 1).