MTHFD1 and cancer: The MTHFD1 rs2236225 AA genotype was associated with an increased risk of cancers (GG vs. AA, OR = 1.83, 95%: 1.02–3.28, p = 0.073; in dominant model GG vs. GA-AA, OR 1.53, 95%: 1.03–2.25, p = 0.033, AIC = 605.8; and in log-additive model OR = 1.37, 95%: 1.04–1.81, p = 0.024, AIC = 605.2).