Multiple in vitro studies have demonstrated that the process of epithelial-to-mesenchymal transition (EMT), a pivotal step for cancer progression with tumor invasion and distant metastasis, is activated by proinflammatory cytokines including TNFα, IL-6, IL-8, and IL-1β [106,107,108,109,110]. This evidence concerns the gene CXCL8 and neoplasm.