There is one recent review on this topic that covered the role of immune cells in the liver and how m6A modification regulates immune cells and genes in lipid homeostasis in the liver as implicated by studies with overexpression of fat mass and obesity associated (FTO), a m6A ‘eraser’, in HepG2 cells [35]. The gene discussed is FTO; the disease is obesity due to melanocortin 4 receptor deficiency.