These findings were observed in 14 genes implicated in inherited retinal diseases (IRDs), which were categorized into four groups: (1) proteins with overrepresentation of missense variants (SAMD11, ALMS1, WFS1, RP1L1, KCNV2, and ADAMTS18), (2) transmembrane transport (CNGB1, CNGA1, TRPM1, ABCA4, BEST1, and KCNV2), (3) internal or structural proteins of the photoreceptors that are essential in visual function (RHO and RPE65), and (4) secreted proteins (TIMP3 and ADAMTS18) [4]. The gene discussed is ADAMTS18; the disease is respiratory distress syndrome in premature infants.