Regarding the involvement of this miRNA in HCC, it has been found that the overexpression of miR-20b-5p facilitates proliferation, migration, and invasion and suppresses the apoptosis of malignant cells [51] and that LncRNA WWOX-AS1 sponges miR-20b-5p in HCC, repressing its progression by upregulating WWOX [52]. This evidence concerns the gene WWOX and hepatocellular carcinoma.