In people, the discovery in 1987 of the gene encoding dystrophin (DMD), responsible for X-linked Duchenne and Becker muscular dystrophy, paved the way for identifying and characterizing the role of many other sarcolemmal and extracellular matrix proteins, such as the sarcoglycans and laminin α2, and their own roles in other forms of muscular dystrophies [1]. Here, DMD is linked to muscular dystrophy.