Although small duplications that include the CHRNA7 gene are frequently detected in microarray studies and have been associated with a wide spectrum of neurodevelopmental phenotypes, including ASD, ID/DD, ADHD, OCD and epilepsy, their relatively high prevalence in the general population makes their interpretation difficult, even more so in the prenatal setting [32]. This evidence concerns the gene CHRNA7 and attention deficit-hyperactivity disorder.