CD4 and acute coronary syndrome: In a study that compared the ultrasonographic characteristics of coronary atheromatous plaques in 66 HIV patients with acute coronary syndrome with those of 120 non-HIV patients, patients reported higher rates of soft, non-calcified plaques with features of instability in HIV patients, which were associated with higher rates of adverse cardiovascular events and recurrent ACS, especially for patients with CD4+ values ≤ 200 cells/mm3 [27].