A study that analyzed certain CVRF for patients with HIV infection with a CD4+ nadir < 350 cells/mm3 pointed out a statistically significant higher prevalence of dyslipidemia, but a non-significant higher prevalence of hypertension and diabetes mellitus compared to HIV patients with a nadir of CD4+ ≥ 350 cells/mm3 [33]. This evidence concerns the gene CD4 and HIV infectious disease.