CD4 and celiac disease: Conversely, MEITL is less frequently associated with coeliac sprue, as is the HLA-DQ2/HLA-Dq8 haplotype [7], and is characterized by a monomorphic infiltrate of small- to medium-sized lymphoid cells expressing CD3+, CD4−, CD8+, CD56+, and TCRβ+ with CD30 negativity associated with an absence of villous atrophy [8].