MAP2K7 and fibrosarcoma: Additionally, PGG was shown via molecular docking to interact with vascular endothelial growth factor (VEGF) signaling molecules, VEGF-A,VEGF receptor (VEGFR-2), protein kinase C (PKC), rapidly accelerated fibrosarcoma (RAF), mitogen activated protein kinase (MEK), extracellular signal regulated kinase (ERK), and protein kinase B (AKT) with binding affinities of −7.9, −8.3, −8.6, −3.7, 10.1, −9, and −10.8 kcal/mol, respectively [35].