CRP spontaneously increases during the first three days of life in a great number of healthy neonates or in babies with non-infective conditions, like a stressful delivery, prolonged labor, meconium aspiration syndrome, delayed transition after birth, prolonged rupture of membranes, hemolysis, intraventricular hemorrhage, or perinatal asphyxias [45,47,116]. This evidence concerns the gene CRP and Intraventricular hemorrhage.