COQ2 and myoclonic epilepsy: Other fatal neonatal or infantile cases resulting from COQ2 mutations included a two-month-old infant with myoclonic epilepsy and hypertrophic cardiomyopathy, resulting from a [c.326G>A] [p. Ser109Asn] COQ2 mutation, who subsequently died at 5 months despite supplementation with CoQ10 (5 mg/kg/day) [34], and a fatal case of a newborn with multi-organ failure resulting from a [c.545T>G] [p.Met182Arg] COQ2 mutation [35].