The better wound healing activity of Raydel OSO is strengthened by the earlier report deciphering the impact of ozone therapy on diabetic foot ulcers by the cellular induction of vascular endothelial growth factor (VEGF), platelets-derived growth factors (PDGF), and transforming growth factor-β (TGF-β) [13]. The gene discussed is TGFB1; the disease is diabetic foot.