Finally, interesting future research could also be related to the effects of chronodisruption (social jetlag, sleep deprivation, etc.)and obesity, which are two main features of our present society, on the oxidative stress-related biological rhythms; and to also study if some part of the beneficial effects of AOXs (i.e., GSPE) could be hypothetically mediated by the reset or re-synchronization of the inner clock-machinery both at central and peripheral levels. Here, CLOCK is linked to obesity due to melanocortin 4 receptor deficiency.