BNIP3 and myotonic dystrophy type 1: Additionally, the increase of mitochondrial fission (phosphor-DRP1Ser616), autophagic and mitophagic markers (BNIP3 and Parkin) in DM1 models (Figure 4) allow us to think that basal autophagy might be triggered, but it is not enough to conduct the clearance of dysfunctional mitochondria and needs to be enhanced.