The expression of p53, MDM2, p21, p38, PI3K/AKT/mTOR, Bcl-2/Bax, STAT3 and STAT5, Nf-kB, Caspase 3-8-9, CREB, ERK/MAP, p70 S6, JNK, ATM, Chk1, Chk2, and H2AX proteins in lysate samples of Jurkat tumor cells were studied using Luminex technology with the MILLIPLEX® MAP 9-Plex Multi-Pathway 9-plex Magnetic Bead Kit. The gene discussed is CREB1; the disease is neoplasm.