Four patients with SRMA had extremely high IL-31 levels above 437.9 pg/mL (corresponding to the maximum IL-31 level in dogs with atopic dermatitis serving as a positive control group), and six dogs with SRMA revealed relatively low IL-31 levels in serum below 80.73 pg/mL (corresponding to the mean IL-31 level in the healthy control serving as a negative control group). Here, IL31 is linked to atopic eczema.