Replacement of secondary Escherichia coli infection in gut by increase in Lactobacillus strain. Inhibition of intestinal damage and tight junctions. Lower serum malondialdehyde. Suppression of mRNA expression of IFN-γ, TNF-α, IL-22, IL-17A, IL-6, and IL-1β [120]. The gene discussed is IL1B; the disease is escherichia coli infection.