Although most G6PD patients do not normally present clinical manifestations, RBCs from these patients present lower levels of NADPH and are more susceptible to oxidative stress (Figure 2 G6PD panel) induced by the action of drugs, anesthetics, infections, and metabolic disturbances [157,158,159,160], leading to hemolytic anemia and various health complications (reviewed in [156,157]). The gene discussed is G6PD; the disease is infection.