GPT and liver disorder: Based on recommendations from the American Association for the Study of Liver Diseases (AASLD), patients with compensated liver disease who are hepatitis B e-antigen (HBeAg)- positive with HBV DNA levels greater than 20,000 IU/mL after a 3- to 6-month period of elevated alanine aminotransferase (ALT) levels greater than two times the upper limit of normal should be considered for antiviral treatment [19].